The Role of Olfactory System in the Etiogenesis of Parkinson’s Diseases: An Overview

Autor:	Jiju Narayanan Avanipully, Dithu Thekkekkara, Sahyadri M, Vipan K. Parihar, Santhepete Nanjundaiah Manjula
Rok vydání:	2022
Předmět:	Pharmacology Pharmacology (medical)
Zdroj:	Journal of Pharmacology and Pharmacotherapeutics. 13:31-39
ISSN:	0976-5018 0976-500X
DOI:	10.1177/0976500x221085802
Popis:	Parkinson’s disease (PD) mainly affects the dopaminergic neuronal networks of the substantia nigra, which leads to both motor and nonmotor symptoms of the disease. Based on the reports from the previous studies, 95% of the cases are presented along with olfactory dysfunction. The relevant publications from 2002 to 2021 were searched and shortlisted using PubMed and Google Scholar. In this review, we have discussed the correlation between olfactory dysfunction and PD. Olfactory damage presents earlier than the motor symptoms. Because there are no current methodologies for the early detection of PD, olfactory dysfunction can be used as a potential marker for the early detection of PD and hence paving the way for better therapeutic approaches.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c971d70290a26468f92b2d51969b52e6 https://doi.org/10.1177/0976500x221085802 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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