Transitions between Sleep Stages in Healthy Humans

Autor: G. V. Kovrov, S. I. Posokhov, A. N. Gerasimov, I. M. Zavalko
Rok vydání: 2020
Předmět:
Zdroj: Neuroscience and Behavioral Physiology. 50:593-598
ISSN: 1573-899X
0097-0549
Popis: We report here an analysis of the durations of segments of sleep stages and interstage transitions with the aim of identifying patterns of sleep development in healthy people. A segment of a stage is a period of sleep from the moment of onset of the stage of interest to the moment at which it is replaced by another stage. The analysis included segments of sleep stages noted on the hypnograms of 70 polysomnography traces from the sleep of six healthy people in the experimental conditions of the Mars 500 project. It has been suggested that the appearance of one or another sleep stage may be linked with the duration of the preceding stage. The studies reported here showed that the durations of segments of all sleep stages overall, with the exception of stage 3, were random, where interruption of segments was independent of their preceding duration. Stage 3 had low stability in the fi rst 2.5 min of occurrence, which increased the probability of its termination; when it lasted longer, the process of interruption started to be random. The interstage transitions studied here established that the occurrence of waking or shallow sleep (stage 1) from stage 3 or REM sleep had a high probability after prolonged periods in these states. Other interstage transitions were random. We suggest that increases in the durations of δ-sleep segments and the stage with rapid eye movements could lead to the development of arousal processes. Further analysis of the longest δ-sleep and REM sleep segments may have potential for constructing mathematical models of sleep and studies of arousal processes during sleep and the mechanisms of their impairments.
Databáze: OpenAIRE
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