Meningoencephalitis caused by concurrent infection with canine distemper virus and a unique Sarcocystis sp. in a gray fox
| Autor: | Sarita Neupane, James F. X. Wellehan, April L. Childress, Eric R. Snook, Brian F. Porter |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Veterinary Diagnostic Investigation. :104063872311697 |
| ISSN: | 1943-4936 1040-6387 |
| Popis: | A deceased 9-wk-old male gray fox ( Urocyon cinereoargenteus) with a history of decreased ambulation and diarrhea was submitted to the Texas A&M Veterinary Medical Diagnostic Laboratory. No significant gross findings were evident on postmortem examination. Histologically, the cerebrum and brainstem had mild necrotizing meningoencephalitis with protozoal schizonts and merozoites. Additionally, glial cells contained intracytoplasmic and intranuclear viral inclusion bodies. Sections of the cerebrum were positive for canine distemper virus (CDV) and negative for Sarcocystis neurona on immunohistochemistry. Bayesian analysis revealed that this Sarcocystis sp. clustered most closely with a clade of unnamed Sarcocystis sp. found in viperid snakes, with a posterior probability of 99%. CDV likely played a significant role in the expression of clinical sarcocystosis in this gray fox. |
| Databáze: | OpenAIRE |
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