Implantable fluorescent hydrogel for continous blood glucose monitoring

Autor:	Shoji Takeuchi, Teru Okitsu, N. Yamamoto, Yukiko Tsuda, H. Shibata, Tetsuro Kawanishi
Rok vydání:	2009
Předmět:	Blood glucose monitoring Glucose sensitivity Materials science medicine.diagnostic_test Fluorescence chemistry.chemical_compound chemistry In vivo Acrylamide Self-healing hydrogels medicine Fluorescent glucose biosensor Biosensor Biomedical engineering
Zdroj:	TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference.
DOI:	10.1109/sensor.2009.5285817
Popis:	We present a continuous glucose monitoring sensors using glucose-sensitive fluorescent dyes. We prepared microgels by copolymerizing acrylamide with the glucose sensitive fluorescent dyes. This fluorescent gel shows a high quantifiability and rapid response in the physiological glucose concentration range of 62.5 to 1000 mg/dL. Our in vivo study revealed that fluorescent intensity of the gels changed in response to in vivo blood-glucose levels. We expect this method to be useful in the development of implantable continuous monitoring systems based on fluorescent gels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c9578ffca07df06fe587f682a514ca10 https://doi.org/10.1109/sensor.2009.5285817 Zobrazit plný text záznamu