Blood Trauma in Plastic Haemodialysis Cannulae
Autor: | J. Y. De Vos, D De Wachter, Pascal Verdonck, R Hombrouckx |
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Rok vydání: | 1997 |
Předmět: |
medicine.medical_specialty
In vitro test business.industry digestive oral and skin physiology 030232 urology & nephrology Biomedical Engineering Medicine (miscellaneous) Bioengineering General Medicine 030204 cardiovascular system & hematology equipment and supplies Haemolysis Cannula Surgery Biomaterials 03 medical and health sciences surgical procedures operative 0302 clinical medicine medicine Dialysis (biochemistry) business therapeutics |
Zdroj: | The International Journal of Artificial Organs. 20:366-370 |
ISSN: | 1724-6040 0391-3988 |
DOI: | 10.1177/039139889702000702 |
Popis: | To investigate the haemolysis in haemodialysis cannulae, an in-vitro set up is built, using a unipuncture dialysis system. This system is connected to a bag with fresh calf's blood, by the cannula under test, mounted in a large bloodline (5mm diameter). The blood characteristics are kept constant by means of a bicarbonate dialysate in the dialyser. During a 6h period, haematological parameters are regularly sampled. Flow through the cannulae is recorded, which is about 500mUmin. Four different cannulae are tested and compared to the results obtained without any cannula in the circuit. In all cases a linear increase in plasma free haemoglobin levels is found after 6h. The cannulae can be ranked from 8F catheter over 13G, 14G to 16G cannula, the latter producing the highest degree of haemolysis. When using plastic cannulae at high blood flows, their haemolytic effect may not be neglected. |
Databáze: | OpenAIRE |
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