| Autor: |
Kuo Ching-Chuan, Shiao Hui-Yi, Amancha Prashanth Kumar, Hsieh Hsing-Pang, Horng Jim-Tong, Hsu John T.-A., Liao Chun-Chen, Chang Sui-Yuan, Shih Shin-Ru, Chao Yu‐Sheng |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Journal of the Chinese Chemical Society. 59:1548-1554 |
| ISSN: |
0009-4536 |
| DOI: |
10.1002/jccs.201200233 |
| Popis: |
An efficient, mild and scalable synthesis of angelicin scaffold based compounds was developed. Particularly, the new synthetic route described here circumvents the need for the previously reported key Fries rearrangement step, which uses impractically harsh conditions. The new methodology is applied to the synthesis of several, previously reported analogs of angelicin which have potent anti-influenza and anti-cancer activities. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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