THIS ARTICLE HAS BEEN RETRACTED: Early recovery, cognitive function and costs of a desflurane inhalational vs. a total intravenous anaesthesia regimen in long-term surgery

Autor: S. Schuler, Swen N. Piper, K. D. Röhm, Joachim Boldt, S. W. Suttner
Rok vydání: 2005
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 50:14-18
ISSN: 0001-5172
DOI: 10.1111/j.1399-6576.2006.00905.x
Popis: Background: The purpose of the study was to compare time of recovery, return of cognitive function, post-anaesthetic care unit (PACU) stay and costs of a propofol/remifentanil (TIVA) with a desflurane/fentanyl-based anaesthesia (desflurane group) in surgical procedures lasting more than 150 min. Methods: Forty-nine patients undergoing elective abdominal prostatectomy were allocated randomly to receive bispectal index (BIS)-controlled desflurane/fentanyl (n = 24) or propofol/remifentanil (n = 25). Awakening, clinical recovery, direct drug acquisition and post-operative pain treatment were documented. Cognitive skills were tested using the Mini-Mental Status (MMST) test. Results: Extubation was significantly faster with desflurane (6.9 ± 3.5 min) than with TIVA (11.2 ± 4.0 min) as well as times for stating name and date of birth (desflurane: 6.1 ± 3.9 and 6.6 ± 4.0 min; TIVA: 12.4 ± 11.5 min and 13.4 ± 11.3 min). There were no significant differences in PACU discharge times or MMS scores between the groups. Significantly more patients suffered post-operative nausea and vomiting (PONV) in the desflurane (33% vs. 0%) than the TIVA group. Overall costs were significantly higher in the TIVA (58.8 ± 11.6 €) than in the desflurane group (35.0 ± 5.7 €). Conclusion: Patients undergoing prolonged surgical procedures showed a faster early recovery after desflurane/fentanyl than using TIVA, whereas stay in the PACU and recovery of cognitive function were similar in both groups. Costs of a TIVA regimen were significantly higher than using a desflurane-based anaesthesia technique.
Databáze: OpenAIRE
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