| Popis: |
The theory and design ofa new planar surface plasmon resonance probe are presented. The new sensoris based on a folded light pipe combined with a telecentric lens. The inexpensive sensing elements areconstructed from pieces ofmicroscope slide and are easy to manufacture. A prototype probe designcapable of measuring 2 samples simultaneously was constructed. This is the first SPR probe capable ofmultiplexing and first order sensing. Initial experimental refractive index testing for 0% to 41% byweight glucose solutions exhibited a sensitivity of3 x i0 index ofrefraction units. Key Words Surface Plasmon Resonance, Refractometer, Biosensor, Process Control, Multiplexing Introduction Sensors based on surface plasmon resonance (SPR) have become popular laboratory tools forapplications such as the monitoring ofimmuno-assays and enzyme reactions'. In addition to bio-chemical sensing, SPR sensors have also been shown to function as high resolution refractometers2.There is potential for utilizing these sensing abilities in industrial process control applications such asenvironmental waste stream monitoring, pharmaceutical production, and food/beverage preparation.Although several trial studies3 have been published, to date there have been no reports of SPR sensorssuccessfully performing in a commercial process control application.For use in commercial process control, a sensor must be compatible with the operating conditions of theapplication and have a low failure rate. Additional necessary sensor characteristics include |
