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AimTo compare the anticalculus efficacy of an experimental dentifrice (0.454% stabilized stannous fluoride/ sodium hexametaphosphate) with a negative control.Methods and MaterialsThis was a randomized, examiner-blind, parallel group study. After a three-month run-in, qualifying subjects were randomized to the experimental or control dentifrice to use twice a day for six months. Volpe-Manhold Index (V-MI) and oral soft tissue examinations were conducted at baseline, three, and six months. Additional analyses were performed separately at three and six months on three subgroups categorized into high, medium, and low calculus-forming subjects.ResultsCompared to the control group, the experimental dentifrice group had a mean calculus score statistically significantly lower at both three months (50%) and six months (55%) post-treatment (pConclusionThe experimental dentifrice revealed significant anticalculus efficacy compared to the control regardless of levels of baseline calculus formation.Clinical SignificanceThe stannous fluoride/sodium hexametaphosphate dentifrice technology is an effective calculus inhibitor for home care.CitationWinston JL, Fiedler SK, Schiff T, Baker RA. An Anticalculus Dentifrice with Sodium Hexametaphosphate and Stannous Fluoride: A Six-month Study of Efficacy. J Contemp Dent Pract 2007 July;(8)5:001-008. |