Measuring acute phase proteins (haptoglobin, ceruloplasmin, serum amyloid A, and fibrinogen) in healthy and infectious bursal disease virus-infected chicks

Autor:	Malihe Masoudian, S. A. Hoseinian, H. Dadras, Maryam Ansari-Lari, S. Nazifi
Rok vydání:	2009
Předmět:	animal structures biology Amyloid Haptoglobin Acute-phase protein medicine.disease Fibrinogen Pathology and Forensic Medicine Infectious bursal disease Blood chemistry embryonic structures Immunology biology.protein medicine Serum amyloid A Anatomy Ceruloplasmin medicine.drug
Zdroj:	Comparative Clinical Pathology. 19:283-286
ISSN:	1618-565X 1618-5641
DOI:	10.1007/s00580-009-0858-z
Popis:	The present study was conducted to evaluate the changes of acute phase proteins (APPs) in healthy and infectious bursal disease virus (IBDV)-infected chicks. Blood samples were taken from 20 healthy chicks as control group and 45 and 20 chicks with mild and severe clinical signs of IBDV, respectively. Sera were isolated and measurement of haptoglobin (Hp), ceruloplasmin, serum amyloid A (SAA), and fibrinogen were done for all chicks using validated methods. Results showed significant differences in ceruloplasmin and SAA between healthy and infected chicks (P 0.05). It can be concluded that in naturally occurring gumboro, a significant decrease in ceruloplasmin and a significant increase in SAA are expected. Among the APPs measured in this study, SAA appears to be the most sensitive parameter.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c8f83f5718270d218ec12583a0af313a https://doi.org/10.1007/s00580-009-0858-z Zobrazit plný text záznamu Full text from SpringerLink