Speciation of Arsenic Compounds in the Urine of Rats Orally Exposed to Dimethylarsinic Acid Ion Chromatography with ICP-MS as an Element-Selective Detector
| Autor: | Yoshinori Inoue, Ginji Endo, Yukiko Date, Kaoru Yoshida, Hua Chen |
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| Rok vydání: | 1996 |
| Předmět: |
inorganic chemicals
Chromatography integumentary system Chemistry Ion chromatography chemistry.chemical_element Arsenic Compound General Chemistry Mass spectrometry Arsenic acid Trimethylarsine Inorganic Chemistry chemistry.chemical_compound Arsenous acid Inductively coupled plasma mass spectrometry Arsenic |
| Zdroj: | Applied Organometallic Chemistry. 10:707-711 |
| ISSN: | 1099-0739 0268-2605 |
| DOI: | 10.1002/(sici)1099-0739(199611)10:9<707::aid-aoc535>3.0.co;2-m |
| Popis: | A combined ion chromatography (IC) with inductively coupled plasma mass spectrometry (ICP-MS) system as an element-selective detector has been used for the determination of arsenic compounds. Seven arsenic compounds were separated by cation-exchange chromatography. Subsequently, the separated arsenic compounds were directly introduced into the ICP-MS and were detected at m/z=75. Detection limits for the seven arsenic compounds ranged from 0.8 to 3.8 μg AS/l. The IC-ICP-MS system was applied to the determination of arsenic compounds in the urine of dimethylarsinic acid (DMAA)-exposed rats. DMAA was the most abundant arsenic compound detected. Arsenous acid, monomethylarsonic acid and trimethylarsine oxide were also detected. |
| Databáze: | OpenAIRE |
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