High loaded dendrimers with free peripheral groups

Autor:	Jesús A. Valencia-Gallegos, Víctor Martínez-Merino, Mario Moises Alvarez
Rok vydání:	2015
Předmět:	Chemistry Stereochemistry Dendrimer Organic Chemistry Drug Discovery Drug delivery Dendritic architecture Branching (polymer chemistry) Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 56:6803-6806
ISSN:	0040-4039
Popis:	We report the synthesis of dendrons and dendrimers with branching units composed of two parts: a residue with biological activity and a branching molecule. This approach allows better exploitation of the dendritic architecture, giving to the scaffolding structure an ‘active’ role beyond the traditional one and leaving the peripheral groups unaffected and ready for diverse modifications in order to improve their potential performance in the drug delivery scenario.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c8c77d2664916062d90349d75d2f85b7 https://doi.org/10.1016/j.tetlet.2015.10.084 Zobrazit plný text záznamu Full Text from ScienceDirect