Evaluation of europium-doped HA/β-TCP ratio fluorescence in biphasic calcium phosphate nanocomposites controlled by the pH value during the synthesis
| Autor: | Sabine N. Guilhen, Nelson Batista de Lima, Lilia Coronato Courrol, Flávia Rodrigues de Oliveira Silva, Ana Helena A. Bressiani |
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| Rok vydání: | 2016 |
| Předmět: |
Nanocomposite
Inorganic chemistry Biophysics chemistry.chemical_element 02 engineering and technology General Chemistry Thermal treatment Crystal structure 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Phosphate 01 natural sciences Biochemistry Fluorescence Atomic and Molecular Physics and Optics 0104 chemical sciences Ion chemistry.chemical_compound chemistry 0210 nano-technology Europium Luminescence |
| Zdroj: | Journal of Luminescence. 180:177-182 |
| ISSN: | 0022-2313 |
| Popis: | Europium-doped hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP) and biphasic phosphate nanopowders were synthesized by co-precipitation method and their crystal structures and fluorescence properties were investigated depending on the pH of the starting solution. In the range of pH 6–10, HA and β-TCP phases coexist. The β-TCP proportion increased as the pH of the solution decreased, while HA yields decreased. At pH below 6, monophasic β-TCP powder was obtained after thermal treatment. In particular, HA and β-TCP can be used as luminescent materials when activated by Eu 3+ ions in substitution of Ca 2+ ions. Herein, the Eu 3+ ions doped HA and β-TCP phase composition were analyzed in order to investigate the fluorescence emission of the HA, β-TCP and biphasic compounds. Eu-doped HA exhibited a red-orange emission at 575 nm with several minor peaks at 610–640 nm, while Eu-doped β-TCP had an unexpected strong red emission at 610–620 nm and a secondary band at 590–600 nm. In fact, the Eu:β-TCP integrated emission area is almost 20-fold higher than Eu:HA for the same europium ion concentration. These results demonstrate the potential of Eu:β-TCP as biomarker for medical applications, as drug release and targeting based on their luminescent properties. |
| Databáze: | OpenAIRE |
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