Indion 860 catalyzed cascade reaction: a greener approach to functionalized cyclohexanones and their novel analogues

Autor:	S. Vaishaly, M. Srinivasa Rao, G. Dhananjaya, Manojit Pal, K. B. Chandra Sekhar, Ch. Sumanth, K. Shiva Kumar, T. Bhaskar Kumar, Gajanan Botre
Rok vydání:	2013
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Cascade reaction General Chemical Engineering Aryl food and beverages Molecule Organic chemistry General Chemistry Alkyl Open air Catalysis
Zdroj:	RSC Advances. 3:2207
ISSN:	2046-2069
DOI:	10.1039/c2ra23039a
Popis:	An Indion 860 mediated cascade reaction of β-ketoester or 1,3-diketone with alkyl/aryl/heteroaryl aldehydes afforded functionalized cyclohexanones in the open air. The catalyst can be recovered and recycled. Combining this methodology with other reactions in the same pot afforded diversity based novel molecules. Some of the synthesized compounds showed inhibition of PDE4 in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c8ba50c4d0344a7e9cad406762b2395c https://doi.org/10.1039/c2ra23039a Zobrazit plný text záznamu