Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice
| Autor: | Li-Yen Chang, Vunjia Tiong, Kim-Kee Tan, Haryanti Azura Mohamad Wali, Sazaly AbuBakar, Shih Keng Loong, Pooi-Fong Wong, Jing Jing Khoo, Fang-Shiang Lim, Pui-Fong Jee |
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| Rok vydání: | 2021 |
| Předmět: |
040301 veterinary sciences
medicine.drug_class Antibiotics Microbiology 0403 veterinary science Lesion 03 medical and health sciences parasitic diseases medicine 030304 developmental biology 0303 health sciences General Veterinary biology fungi Laboratory mouse virus diseases 04 agricultural and veterinary sciences 16S ribosomal RNA Isolation (microbiology) biology.organism_classification eye diseases Epithelium medicine.anatomical_structure Streptococcus cuniculi medicine.symptom Bacteria |
| Zdroj: | Journal of Veterinary Medical Science. 83:280-284 |
| ISSN: | 1347-7439 0916-7250 |
| Popis: | Corneal lesions appearing as white mass beneath intact epithelium, with ocular discharge in one mouse, was observed in a batch of laboratory-raised BALB/c mice (n=9 of 56). The affected mice remained active, well-groomed and had normal appetite. Isolates recovered from swab cultures of the external and internal contents of the eye had partial 16S rRNA gene sequence of 99.1% similarity to Streptococcus cuniculi. No previous report of S. cuniculi infection in laboratory rodents has been presented. The isolate was susceptible to all antibiotics tested. We suggest S. cuniculi is an opportunistic bacteria in laboratory mice but are uncertain of its source. Our findings revealed that S. cuniculi is able to colonize laboratory mice and should be considered when mice present with eye lesion or ocular discharge. |
| Databáze: | OpenAIRE |
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