Primary soft tissue angiomyolipoma in a dog with unusual clinical features
| Autor: | Jiří Lenz, Petra Konecna, F. Tichý, Luděk Fiala |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Angiomyolipoma General Veterinary 040301 veterinary sciences business.industry 0402 animal and dairy science Perivascular epithelioid cell tumour Soft tissue 04 agricultural and veterinary sciences medicine.disease 040201 dairy & animal science 0403 veterinary science medicine Immunohistochemistry business |
| Zdroj: | Acta Veterinaria Brno. 90:179-183 |
| ISSN: | 1801-7576 0001-7213 |
| DOI: | 10.2754/avb202190020179 |
| Popis: | Angiomyolipoma is an extremely rare neoplasm in animals. It belongs to a group of perivascular epithelioid cell tumours (so-called PEComas). This study reports a case of primary soft tissue angiomyolipoma in a dog with some unusual clinical features. A 4-year old female Labrador dog with a rapidly growing pelvic tumour measuring 30 × 20 cm with a short history of 12 weeks was presented. The tumour was well-circumscribed and pushed into the right vaginal wall and into the perineum. The tumour was completely surgically excised. An extensive histological examination was performed, including immunohistochemical analysis. Histology revealed a mesenchymal neoplasm consisting of three tissue components – mature adipose tissue (which dominated), vessels, and smooth muscle (spindle) cells. The lesion showed positive immunohistochemical staining with smooth muscle actin and desmin in mature-appearing smooth muscle cells and S-100 protein positivity in adipocytes. The diagnosis of angiomyolipoma must be considered in different types of benign and malignant tumours of various lineages. The diagnostic approach to soft tissue tumours, including angiomyolipoma, requires optimal processing and sectioning of resected specimens. This paper is believed to be the first case of primary soft tissue angiomyolipoma reported in the veterinary literature. |
| Databáze: | OpenAIRE |
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