Optimizing halogenation conditions ofN-halamine polymers and investigating mode of bactericidal action

Autor:	John N. Wardell, Gabriel Cavalli, Abd El-Shafey I. Ahmed, Michael E. Bushell, John N. Hay
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Azo compound Polymers and Plastics Chemistry Halogenation Chemical modification General Chemistry Polymer Surfaces Coatings and Films chemistry.chemical_compound Sodium hypochlorite Polymer chemistry Halogen Materials Chemistry Copolymer Antibacterial agent
Zdroj:	Journal of Applied Polymer Science. 113:2404-2412
ISSN:	1097-4628 0021-8995
DOI:	10.1002/app.30390
Popis:	An N-Halamine biocidal polymer was prepared by co-polymerizing toluene-2,6-diisocyanate with a new heterocyclic uramil-based azo-monomer, followed by halogenation. The mode of action of N-halamine polymers on bacteria was investigated and halogenation conditions (temperature, halogenation time, halogen concentration) were optimized for bactericidal action against E. coli and S. aureus. It was found that the mode of action of this type of polymer is a combination of different factors; contact, release, and through interaction of the polymer with the bacterial medium. The most effective halogenation conditions were stirring 1 g polymer in 10 mL sodium hypochlorite (10 %) for 1 h at ambient temperature (22°C). © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Databáze:	OpenAIRE
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