| Popis: |
Simulation studies of adaptive optimising control of continuous biochemical processes are presented. Two different approaches are proposed and compared. The first method, self-tuning extremum control, is based on dynamic model identification and consecutive application of a classical gradient optimisation technique. The second approach applied is the Integrated System Optimisation and Parameter Estimation (ISOPE) method. Two different objective functions, aiming at cellular productivity maximisation and reference error minimisation, respectively, are to be fulfilled. |
