Cerebral ependymoma in a patient with multiple sclerosis

Autor: Michele Acqui, Domenica Di Stefano, Luigi Ferrante, Emanuela Caroli
Rok vydání: 2008
Předmět:
Zdroj: Surgical Neurology. 70:414-420
ISSN: 0090-3019
Popis: Background The concurrence of multiple sclerosis (MS) and brain tumors is a rare but well-recognized condition. The radiologic evidence of the progressive evolution of a mega-plaque in a tumor has never been described. We report the first case of such an occurrence. Methods A 27-year-old woman with a diagnosis of MS was referred to us for an intense frontal headache. Magnetic resonance imaging showed a mass lesion in correspondence of a black hole lesion previously diagnosed. The patient was operated on, with complete removal of the tumor documented by an intraoperative MRI. The histologic examination evidenced an ependymoma. Postoperative radiotherapy was performed. Results The patient is well and recurrence-free at 2 years follow-up. Conclusions The present case, documenting the transformation of a mega-plaque into a tumor, suggests a cause-effect relationship between MS and brain tumors.
Databáze: OpenAIRE