Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus

Autor:	F. S. Rhame, Chap T. Le, John E. Connett, Janet L. Thomas
Rok vydání:	2007
Předmět:	Statistics and Probability Maximum likelihood Human immunodeficiency virus (HIV) General Medicine Biology medicine.disease medicine.disease_cause Virology Virus Blood donor Acquired immunodeficiency syndrome (AIDS) Immunopathology medicine Viral disease Statistics Probability and Uncertainty
Zdroj:	Biometrical Journal. 32:781-789
ISSN:	1521-4036 0323-3847
DOI:	10.1002/bimj.4710320703
Popis:	A method is described for estimating the probability that transfusion of a given quantity of blood from an AIDS-infected donor will result in infection in the recipient. The method is based on maximum likelihood, and requires the assumption that individual viruses act independently in causing infection. Results of simulations indicate that the resulting estimates have low bias. The method is applicable to a wide variety of other problems.
Databáze:	OpenAIRE
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