Rapid Diagnosis of Legionnaires' Disease by Bronchoalveolar Lavage

Autor: William R. Kohorst, Steven A. Schonfeld, Michael E. Whitcomb, James E. Macklin
Rok vydání: 1983
Předmět:
Zdroj: Chest. 84:186-190
ISSN: 0012-3692
Popis: Legionella pneumophila has, in recent years, emerged as a common pulmonary pathogen in the normal and immuno-compromised patient (ICP). Making a specific etiologic diagnosis of pneumonia in the latter group is a common clinical dilemma often complicated by poor specimen availability and risks of invasive procedures. Improved staining and isolation techniques for L pneumophila would suggest that early diagnosis could be possible if adequate specimens were available. This report summarizes our experience with bronchoalveolar lavage (BAL) with which we have diagnosed L pneumophila in eight immunocompromised patients, well in advance of more traditional methods. On the basis of this experience, we would advocate early BAL in the ICP as a rapid, safe, moderately sensitive and specific diagnostic test to aid in the identification of L pneumophila.
Databáze: OpenAIRE