The fetal frontomaxillary facial angle in normal and trisomy 21 ultrasounds at 11-13+6 weeks of gestation: findings among the ethnic Chinese compared with Caucasian

Autor:	Woei Chyn Chu, Ching Hua Hsiao, Wen Liang Liu, Ran Chou Chen, Yin Jiun Tseng, Bo Jen Cheng
Rok vydání:	2013
Předmět:	Gynecology education.field_of_study Fetus medicine.medical_specialty business.industry Population Ethnic chinese Obstetrics and Gynecology Gestational age medicine.disease Standard technique medicine Gestation First trimester ultrasound education business Trisomy Genetics (clinical)
Zdroj:	Prenatal Diagnosis. 33:711-715
ISSN:	0197-3851
Popis:	Objective The aim of this research was to compare the fetal frontomaxillary facial (FMF) angle between normal and trisomy 21 fetuses at 11+0–13+6 weeks gestation in a Chinese population. Methods A prospective observational study was performed that included 640 euploid and 45 trisomy 21 singleton pregnancies undergoing first trimester ultrasound screening between 11 and 13+6 weeks of gestation. The FMF angle was measured in the midsagittal plane using the standard technique. Results The fetal mean FMF angle decreased with the increasing crown-rump length (CRL) from 88.6°at a CRL of 45 mm to 78.5° at a CRL of 84 mm (FMF angle = 100.212 − 0.258 × CRL, R2 = 0.222, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c8867b903d34f53fe9b9720a0e728554 https://doi.org/10.1002/pd.4084 Zobrazit plný text záznamu Plný text