| Autor: |
A. I. Gómez-Varela, Bastian Carnero, Maria Teresa Flores-Arias, Ezequiel Álvarez, C. Bao-Varela |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC). |
| DOI: |
10.1109/cleo/europe-eqec52157.2021.9592642 |
| Popis: |
Micro-channels of different geometries have been used to simulate blood capillaries as well as bigger vessels such as coronaries [1] , [2] . Some of the authors have reported the fabrication of blood vessel-like model by a combination of laser ablation technique and soft-lithography to obtain a polydimethylsiloxane (PDMS) device fully covered by that remain after flow assays [2] . In the manufacturing process laser based, most of the time is spent in the human umbilical vein endothelial cells (HUVECs)replication of vessel-like with PDMS, being this fact the limiting factor for large scale production. To reduce the fabrication time an alternative could be the use of UV-curable polymers developed for fabricating multiscale, hierarchical structures for the manufacturing of biomedical, and micro/nanofluidic devices [3] . In this work a comparison between the biocompatibility of UV-curable PDMS (KER 4690 A/B (Shin-Etsu Silicones Europe B.V.)) and the thermal curable PDMS (Sylgard 184: Dow Corning Michigan, USA) is presented. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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