Amount, Type, and Timing of Recreational Physical Activity in Relation to Colon and Rectal Cancer in Older Adults: the Cancer Prevention Study II Nutrition Cohort
| Autor: | Ann Chao, Cari J. Connell, Eric J. Jacobs, Marjorie L. McCullough, Alpa V. Patel, Eugenia E. Calle, Vilma E. Cokkinides, Michael J. Thun |
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| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Cancer Epidemiology, Biomarkers & Prevention. 13:2187-2195 |
| ISSN: | 1538-7755 1055-9965 |
| DOI: | 10.1158/1055-9965.2187.13.12 |
| Popis: | Physical activity has consistently been associated with lower risk of colon cancer, but information is limited on the amount, type, and timing of activities. The relationship between physical activity and rectal cancer is unclear. We examined characteristics of recreational physical activity in relation to colon and rectal cancer in the Cancer Prevention Study II Nutrition Cohort of 70,403 men and 80,771 women (median age, 63 years); 940 colon and 390 rectal cancers were identified from enrollment in 1992 to 1993 through August 1999. The multivariate-adjusted rate ratios (95% confidence intervals) associated with any recreational physical activity compared with none were 0.87 (0.71-1.06) for colon cancer and 0.70 (0.53-0.93) for rectal cancer. Colon cancer risk decreased significantly with increasing total hours (P for trend without reference group = 0.007) and metabolic equivalent hours (P for trend = 0.006) per week of activities. No clear decrease in rectal cancer risk was seen with increasing hours per week of physical activity. Rate ratios (95% confidence intervals) were 0.72 (0.52-0.98) for |
| Databáze: | OpenAIRE |
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