Mathematical chromatography solves the cocktail party effect in mixtures using 2D spectra and PARAFAC

Autor:	Henrik Toft, Peter I. Hansen, Rasmus Bro, Søren Balling Engelsen, Nanna Viereck, Marianne Toft
Rok vydání:	2010
Předmět:	Analyte chemistry.chemical_compound Analisis factorial Chromatography chemistry Maltotriose Nuclear magnetic resonance spectroscopy Measure (mathematics) Cocktail party effect Two-dimensional nuclear magnetic resonance spectroscopy Spectroscopy Spectral line Analytical Chemistry
Zdroj:	TrAC Trends in Analytical Chemistry. 29:281-284
ISSN:	0165-9936
DOI:	10.1016/j.trac.2010.01.008
Popis:	The cocktail party effect in analytical chemistry refers to the ability to measure a complex mixture of analytes and to resolve the signals from a single analyte. We describe a new approach that we have coined mathematical chromatography, where data from complex spectra are resolved into pure-analyte information by so-called three-way modeling. Three-way analysis requires the addition of an extra dimension to the signals being acquired. Here, as an example, mathematical chromatography is applied to a series of diffusion-edited 2D NMR spectra of mixtures of glucose, maltose and maltotriose to demonstrate that it is possible to identify and to resolve individual components in highly overlapping 2D NMR spectra.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c8461e9cfc7469c7bf65f9d2950f1237 https://doi.org/10.1016/j.trac.2010.01.008 Zobrazit plný text záznamu Full Text from ScienceDirect