Total Fatty Acids Content of Erythrocyte Membrane Phospholipids in Healthy Children from Birth to 6 Years Old

Autor: Francisco Rodríguez Leyva, Talia Mondragón-Velásquez, Sara Montaño-Benavides, Marco Antonio García-Casasola, María del Socorro Santiago-Sánchez, Sagrario Millian, Elba Beltrán-Murguia, Irma Quintero-Montoya, Irma Sofía Ladrón De Guevara, José Luis Silencio-Barrita
Rok vydání: 2015
Předmět:
Zdroj: International Journal of Pediatrics and Child Health. 3:21-30
ISSN: 2311-8687
DOI: 10.12974/2311-8687.2015.03.01.4
Popis: Objective: Relate the profile of total fatty acids in erythrocyte membrane with the child nutritional status. Method: It was determined the concentration of total fatty acids in erythrocyte membrane of 138 children under 6 years (69girls, 69children) through a blood sample (2mL) by capillary gas chromatography. Likewise assessed the status through Anthropometry, Dietetics and clinical nutrition. Results: 33 fatty acids were found in the erythrocyte membrane: 14 saturated, 8 monounsaturated, 11 Polyunsaturated and 2 Trans fatty acids. The SFA had the highest concentration, especially Palmitic acid with 22.9mg/100mL in children. DHA showed a concentration of 6.3mg/100mL and the EPA of 1.2mg/100mL, showing a positive correlation (r = 0.55) statistically significant (p < 0.002). The n-6 PUFAS showed statistically significant difference (p < 0.001) between the age groups, of the total sample BMI/age values showed variable Z score from scratch, according to WHO, but have values indicating malnutrition, with a tendency to overweight and obesity. This trend is higher in boys than in girls. The dietary intake of nutrient show great variability in girls, with statistically significant differences (p < 0.05, 95% CI) between the age groups for energy, total fat, SFA and MUFA. In Children, only fiber has statistically significant differences. Conclusions: The concentration of the measured fatty acids remains constant in the erythrocyte membrane and apparently is not modified with respect to the age. These values are low in Mexican children.
Databáze: OpenAIRE