Influence of angiotensin II and mannitol on local renal blood flow
Autor: | K. König, Sökeland J, P. May, K. Bihler |
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Rok vydání: | 1969 |
Předmět: | |
Zdroj: | Urology and Nephrology. 1:373-380 |
ISSN: | 1573-2584 0301-1623 |
Popis: | The present report outlines investigations in experimental animals (dogs) conducted for the purpose of studying the effect of angiotensin II and 10% mannitol solution on local renal blood flow. Most of the experiments were carried out in normovolaemic conditions, a few of them in haemorrhagic shock. Following the description of the experimental set-up and the procedure employed, the response of the arterial blood pressure and the local renal blood flow to mannitol infusion in normovolaemia is delineated with the help of a tabular summary. Experiments in haemorrhagic shock seem to suggest that concurrent intravenous administration of mannitol and angiotensin II in acute hypotensive circulation is warranted if preceding volume replacements have not yielded an adequate stabilizing effect on the circulation. |
Databáze: | OpenAIRE |
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