Fibrillary glomerulonephritis in a patient with familial sensorneural deafness

Autor:	Hirofumi Makino, Masami Hashimoto, Shuji Ikeda, Kenichi Shikata, Kazue Hironaka, Yoshio Nagake, Haruo Ichikawa
Rok vydání:	1997
Předmět:	Pathology medicine.medical_specialty Proteinuria medicine.diagnostic_test business.industry Fibrillary Glomerulonephritis Bilateral sensorineural deafness General Medicine Sensorineural deafness Amyloid fibril Serology Nephrology Medicine Renal biopsy medicine.symptom Family history business
Zdroj:	Nephrology. 3:381-384
ISSN:	1440-1797 1320-5358
Popis:	Summary: A 47-year-old woman was admitted to the hospital for evaluation of proteinuria. Bilateral sensorineural deafness had been diagnosed previously at age 35. She had a positive family history of deafness going back three generations. A renal biopsy showed the presence of highly organized fibrillary deposits in the subendothelial mesangial areas. the microfibrils had a diameter of 11-16 nm, larger than the diameter of amyloid fibrils, and did not have a microtubular appearance. the renal specimen was negative for Congored staining. There was no clinical or serologic evidence of paraproteinaemia, cryoglobulinaemia, light-chain disease, or systemic lupus erythematosus. the diagnosis was fibrillary glomerulonephritis. This is the first known case of fibrillary glomerulonephritis in a patient with familial sensorineural deafness.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c7fc15dea0a159e80c807e3f4ca5563b https://doi.org/10.1111/j.1440-1797.1997.tb00259.x Zobrazit plný text záznamu Plný text