Pneumocystis jiroveciiInfections Among COVID-19 Patients: A Case Series and Literature Review

Autor: Paul Amstutz, Nathan C Bahr, Karen Snyder, D Matthew Shoemaker
Rok vydání: 2023
Předmět:
Zdroj: Open Forum Infectious Diseases. 10
ISSN: 2328-8957
DOI: 10.1093/ofid/ofad043
Popis: BackgroundPneumocystis jirovecii pneumonia (PCP) is a serious, emerging complication of coronavirus disease 2019 (COVID-19).MethodsWe performed a systematic review of published cases. We describe 6 new cases of PCP/COVID-19 coinfection. Among our cases (n = 6) and those in the literature (n = 69) with available data, the median age (interquartile range [IQR]) was 59 (44–77) years (n = 38), 72% (47/65) were male, and the mortality rate was 30.9% (21/68).ResultsLong-term corticosteroid use was noted in 45.1% (23/51), advanced HIV infection (defined as a CD4 count ConclusionsThese findings suggest a need for greater attention to PCP risk factors among COVID-19 patients and consideration of PCP prophylaxis in these high-risk populations.
Databáze: OpenAIRE