A Biomimetic Artificial Disc with Improved Mechanical Properties Compared to Biological Intervertebral Discs

Autor: Kiyoshi Kaneda, Kuniyoshi Abumi, Yoshihisa Kotani, Yasuo Shikinami, Bryan W. Cunningham
Rok vydání: 2004
Předmět:
Zdroj: Advanced Functional Materials. 14:1039-1046
ISSN: 1616-3028
1616-301X
DOI: 10.1002/adfm.200305038
Popis: Patients with serious spinal disc disorders will benefit from a novel artificial disc system that is suitable for clinical use in replacement arthroplasty. The disc is composed of a biomimetic three-dimensional (3D) fabric with a triaxial fiber alignment that has superior mechanical properties when compared to conventional implants. This disc improves on the constitutional imperfections of biological intervertebral discs by eliminating the risk of rupture and delamination. The fabric bonds firmly to disc bodies, and functions in combination with bioactive bioresorbable pins and scaffolds as a stand-alone system that maintains the position of the disc and promotes bone growth at the interface. The disc has high biocompatibility and can maintain biomimetic “J-shaped” stress–strain behavior for up to sixty-three million alternating stresses, which is the equivalent of natural biological movements for a period of more than 30 years. This technology exemplifies how, in the best biomaterials, biological flexibility may occasionally overcome artificial rigidity.
Databáze: OpenAIRE
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