Extracellular volume fraction determined by equilibrium contrast-enhanced computed tomography: correlation with histopathological findings in gastric cancer

Autor: Yusuke Nishimuta, Daisuke Tsurumaru, Satohiro Kai, Junki Maehara, Yoshiki Asayama, Eiji Oki, Kousei Ishigami
Rok vydání: 2023
Předmět:
Zdroj: Japanese Journal of Radiology.
ISSN: 1867-108X
1867-1071
DOI: 10.1007/s11604-023-01393-3
Popis: Purpose To assess the relationship between histopathological features of gastric cancer and the extracellular volume fraction (ECV) measured by preoperative equilibrium contrast-enhanced computed tomography (CECT). Materials and methods The study group consisted of 66 patients with surgically resected gastric adenocarcinoma who underwent preoperative multiphasic CECT. Tumor ECVs were calculated using region-of-interest measurements within the gastric cancer and aorta of each case on unenhanced and equilibrium-phase images. The relationship between the mean ECV values and clinicopathological parameters was examined by univariate analysis. Parameters showing a significant difference in the former test were further tested by linear regression and receiver operating characteristic (ROC) curve analyses. Results In the univariate analysis, the values of venous invasion (p = 0.0487) and tumor infiltration (INF) pattern (p β = 0.57, p Conclusion Tumor ECV determined by equilibrium CECT is significantly correlated with the pathological INF of gastric cancer.
Databáze: OpenAIRE
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