Wound healing

Autor: J.W. Shupp, S. Tejiram, A. Barbul, S.L. Kavalukas
Rok vydání: 2016
Předmět:
DOI: 10.1016/b978-1-78242-455-0.00001-x
Popis: Repair of an injured organ depends upon a complex physiologic process involving inflammatory cell migration, cytokine production, extracellular matrix deposition, and scar remodeling. Wound healing can be divided into four general phases that include hemostasis, an inflammatory response, remodeling, and maturation. There are a variety of wound types, both acute and chronic, that require their own specific method of treatment. The resulting scars that form include hypertrophic and keloid scars that require a wide variety of treatment modalities. A burn injury represents a special kind of injury and wound healing that requires a multidisciplinary approach to management. Finally, this work looks at current animal models and wound types used in research to explore and discover new treatment modalities, including novel biomaterials, and strategies.
Databáze: OpenAIRE