Functional activity of hemopoietic and stromal cells in various types of myelodysplastic syndrome

Autor:	T. E. Manakova, A. S. Kozlovskaya, L. P. Gerasimova, E. A. Lukina, Tsvetaeva Nv
Rok vydání:	1999
Předmět:	Haematopoiesis Stromal cell medicine.anatomical_structure Chemistry Precursor cell Cancer research Lymph node stromal cell medicine Functional activity General Medicine Bone marrow Bone marrow cell General Biochemistry Genetics and Molecular Biology
Zdroj:	Bulletin of Experimental Biology and Medicine. 127:10-13
ISSN:	1573-8221 0007-4888
Popis:	Using clonal methods for assessment of hemopoietic and stromal cells and long-term bone marrow cell cultures, we have demonstrated heterogeneity of myelodysplastic syndrome. Low content of stromal precursor cells in native bone marrow, peculiarities in the formation of the stromal layer and its hemopoiesis-stimulating capacity in long-term cultures, and altered properties of stromal precursor cells in long-term cultures indicate defect in the stromal microenvironment in myelodysplastic syndrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c7d46e4b73b496da4ebada3d6cfca8ea https://doi.org/10.1007/bf02432789 Zobrazit plný text záznamu Full text from SpringerLink