Stereoselective quantitative analysis of ranolazine in plasma and tissue samples: application in pharmacokinetics and tissue distribution studies

Autor: Yuanyuan Zhu, Hong Zhang, Siman Ma, Lizhi Miao, Ge Jin, Jiahui Li, Tohutanguli Nuerkaman, Qiruo Sun, Yang Liu, Shiliang Yin
Rok vydání: 2022
Předmět:
Zdroj: New Journal of Chemistry. 46:16547-16555
ISSN: 1369-9261
1144-0546
DOI: 10.1039/d2nj02302d
Popis: This study aimed to develop a rapid and sensitive reversed-phase mode high-performance liquid chromatography-electrospray ionization coupled with a tandem mass spectrometry method for the simultaneous determination of ranolazine enantiomers in rat plasma and tissues.
Databáze: OpenAIRE