| Autor: |
Andrea Gonzalez-Montoro, Julio Barbera, David Sanchez, Alvaro Mondejar, Marta Freire, Karel Diaz, Alejandro Lucero, Santiago Jimenez-Serrano, Jorge Alamo, Constantino Morera-Ballester, John Barrio, Neus Cucarella, Victor Ilisie, Laura Moliner, Celia Valladares, Antonio J. Gonzalez, John Prior, Jose M. Benlloch |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Bio-Algorithms and Med-Systems. 18:107-119 |
| ISSN: |
1896-530X |
| Popis: |
In this article, we present the geometrical design and preliminary results of a high sensitivity organ-specific Positron Emission Tomography (PET) system dedicated to the study of the human brain. The system, called 4D-PET, will allow accurate imaging of brain studies due to its expected high sensitivity, high 3D spatial resolution and, by including precise photon time of flight (TOF) information, a boosted signal-to-noise ratio (SNR). The 4D-PET system incorporates an innovative detector design based on crystal slabs (semi-monolithic) that enables accurate 3D photon impact positioning (including photon Depth of Interaction (DOI) measurement), while providing a precise determination of the photon arrival time to the detector. The detector includes a novel readout system that reduces the number of detector signals in a ratio of 4:1 thus, alleviating complexity and cost. The analog output signals are fed to the TOFPET2 ASIC (PETsys) for scalability purposes. The present manuscript reports the evaluation of the 4D-PET detector, achieving best values 3D resolution values of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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