Palladium mediated substitutions and rearrangements in spiro[4,4]nonanes

Autor:	Kjell Undheim, Doina Sirbu, Mette Lene Falck-Pedersen, Christian Rømming
Rok vydání:	1999
Předmět:	Allylic rearrangement chemistry.chemical_compound Chemistry Organic Chemistry Drug Discovery Diol chemistry.chemical_element Biochemistry Medicinal chemistry Palladium
Zdroj:	Tetrahedron. 55:6703-6712
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(99)00316-6
Popis:	The two-step NaBH 4 CeCl 3 1,2-reduction of spiro[4,4]nonane-2,7-diene-1,6-dione gave a rans-alcohol as a first product which reacted further to the corresponding cis,trans-diol. Pd(II)-catalysis was used to effect an allylic rearrangement from the 1,6-diacetate to the corresponding 2,7-diacetate. Both diacetates were substrates for Pd(0)-catalyzed allylic alkylations. The relative stereochemistry was retained.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c7aca261434d78aeff3c021c7df67066 https://doi.org/10.1016/s0040-4020(99)00316-6 Zobrazit plný text záznamu Full Text from ScienceDirect