Blastic plasmacytoid dendritic cell neoplasm in a young female: Rare and challenging

Autor:	Ketan Modak, Vivek S. Radhakrishnan, Jeevan Kumar Garg, Deepak Mishra
Rok vydání:	2020
Předmět:	03 medical and health sciences Pathology medicine.medical_specialty 0302 clinical medicine Oncology business.industry 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Medicine Blastic plasmacytoid dendritic cell neoplasm business Young female 030215 immunology
Zdroj:	Indian Journal of Medical and Paediatric Oncology. 41:761-763
ISSN:	0975-2129 0971-5851
Popis:	Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic malignancy with an aggressive behavior, seen commonly in the elderly age group and usually involves the skin. Evaluation, diagnosis, and treatment pose unique challenges with poor outcomes. We report a case of an 18-year-old female who presented with lymphadenopathy and bicytopenia. The diagnosis of BPDCN was an initial challenge. She thereafter received intensive chemotherapy followed by an allogenic partially mismatched sibling donor hematopoietic cell transplantation, only to relapse in a few months. Beginning from the diagnosis, the management of this rare disorder and its relapse until her last followup provided several learning opportunities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c7aa9f5f24067be711bd677c9de5be58 https://doi.org/10.4103/ijmpo.ijmpo_143_19 Zobrazit plný text záznamu Plný text ve formátu PDF