ChemInform Abstract: Phosphonolipids as Non-Viral Vectors for Gene Therapy

Autor:	Herve Des Abbayes, J.‐C. Clement, Gwénaëlle Le Bolc’h, Jean-Jacques Yaouanc, Christine Gable-Guillaume, Virginie Floch, Nathalie Le Bris, Claude Ferec
Rok vydání:	2010
Předmět:	Transfer DNA Haematopoiesis Cell culture Chemistry Genetic enhancement General Medicine Molecular biology Viral vector K562 cells
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199918212
Popis:	Several phosphonates with two fatty chains and different polar heads were synthesized and evaluated for their potential to transfer DNA into epithelial (COS-7) and hematopoietic (K562) cell lines, and compared to commercially available references. In both cases, ammonium-phosphonates were particularly efficient.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c79884d5d5b3600fbfbaa25c11b16ca1 https://doi.org/10.1002/chin.199918212 Zobrazit plný text záznamu Plný text