An investigation of the catalytic potential of mono- and dicationic imidazolium N-heterocyclic carbenes in the benzoin condensation

Autor:	Feray Aydogan, Cigdem Yolacan, Murat Emrah Mavis
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Chain length chemistry Organic Chemistry Drug Discovery Polymer chemistry Imidazole Benzoin condensation Biochemistry Catalysis
Zdroj:	Tetrahedron Letters. 51:4509-4511
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.06.099
Popis:	The catalytic potential of imidazolium salts in the benzoin condensation was investigated. Various aromatic aldehydes were tested in the benzoin condensation under the optimised protocol to afford α-hydroxyketones using N-heterocyclic carbenes derived from mono- and dicationic imidazolium salts. The products were obtained in good yields within short reaction times. Dicationic imidazolium salts with a long aliphatic chain between the imidazole rings were found to be more effective pre-catalysts for the benzoin condensation in comparison to the corresponding monocationic salts having the same aliphatic chain length.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c795c7a641da36d81883b4d6fa7485a3 https://doi.org/10.1016/j.tetlet.2010.06.099 Zobrazit plný text záznamu Full Text from ScienceDirect