Single and serial estimates of amniotic fluid volume and umbilical artery resistance in the prediction of intrauterine growth restriction
| Autor: | Khalid S. Khan, Philip Owen, P. W. Howie |
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| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Amniotic fluid Radiological and Ultrasound Technology Receiver operating characteristic business.industry Obstetrics Ultrasound Obstetrics and Gynecology Intrauterine growth restriction Umbilical artery General Medicine medicine.disease Reproductive Medicine Obstetrics and gynaecology medicine.artery Predictive value of tests medicine Radiology Nuclear Medicine and imaging Amniotic fluid index business |
| Zdroj: | Ultrasound in Obstetrics and Gynecology. 13:415-419 |
| ISSN: | 0960-7692 |
| DOI: | 10.1046/j.1469-0705.1999.13060415.x |
| Popis: | Objectives To determine whether single or serial estimates of both the amniotic fluid index (AFI) or pulsatility index (PI) of the umbilical artery Doppler waveform can usefully identify infants with anthropometric features of intrauterine growth restriction (IUGR). Methods A total of 274 women underwent serial antenatal ultrasound examinations at predetermined intervals. Four biophysical parameters were considered: AFI and PI prior to delivery and change in AFI and PI over a 28-day period in the third trimester. All values were expressed as standard deviation scores. IUGR was diagnosed if the neonate demonstrated skinfold thickness < 10th centile, ponderal index < 25th centile or mid-arm circumference to occipitofrontal circumference (MAC : OFC) < −1 SD. Receiver operator characteristic curves were used to determine an optimal cut-off point, and test performance of the biophysical parameters were expressed as likelihood ratios (LR). Results The test performances of all four ultrasound parameters for any of the three diagnostic criteria for IUGR was poor. The highest positive LR was only 2.5 (95% CI 1.5–4.1) for PI prior to delivery in the prediction of ponderal index < 25th centile. Conclusion Despite positive associations between single and serial estimates of AFI and PI with abnormal neonatal morphometry, the likelihood ratios remained low. The results of this study do not support the use of single or serial estimates of AFI or umbilical artery PI in the prediction of IUGR. Copyright © 1999 International Society of Ultrasound in Obstetrics and Gynecology |
| Databáze: | OpenAIRE |
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