Forever (FGF) 21
| Autor: | Joseph Bass |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Starvation
medicine.medical_specialty Oxidative metabolism FGF21 media_common.quotation_subject Circadian clock Longevity General Medicine Biology Fibroblast growth factor General Biochemistry Genetics and Molecular Biology Endocrinology Internal medicine medicine Adaptation medicine.symptom Reproduction media_common |
| Zdroj: | Nature Medicine. 19:1090-1092 |
| ISSN: | 1546-170X 1078-8956 |
| Popis: | The fibroblast growth factor 21 (FGF21)-β-Klotho pathway orchestrates a switch to oxidative metabolism during fasting and starvation and has been implicated as a signal connecting nutrition, growth, reproduction and longevity. Two new studies in mice show that Fgf21 interacts directly with the brain circadian clock to coordinate activity and reproduction as part of the adaptation to fasting. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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