| Autor: |
Naoaki Hayashi, Shigenobu Jinnouchi, Yasuhiko Sawa, Yasuhiko Kubo, Hiroshi Obata, Tsuneaki Arishima, Kunio Okuda, Yutaka Shimokawa, Masaharu Hashimoto, Eisuke Nagata |
| Rok vydání: |
1977 |
| Předmět: |
|
| Zdroj: |
Gastroenterology. 72:1213-1216 |
| ISSN: |
0016-5085 |
| DOI: |
10.1016/s0016-5085(77)80013-9 |
| Popis: |
Hepatitis B surface antigen was determined in sera of 122 cases of hepatocellular carcinoma seen in Japan, using both the counterimmunoelectrophoresis and radioimmunoassay (RIA) techniques. It was positive in 49.2% of the patients with RIA, but the level of antigen in serum was relatively low since positivity rate by counterimmunoelectrophoresis was only 10.7%. The degree of antigenemia as assessed from the count relative to the cut-off value in RIA, was increased during the clinical course in 75% of the patients. The antigen tended to rise in concentration when the tumor grew at a rapid rate, when damage to liver parenchyma was extensive, or in patients receiving chemotherapy. There was also a tendency for less frequent positive antigen tests in patients with higher α-fetoprotein levels. Illustrative cases are presented with discussion on the possible explanation for the change in the degree of antigenemia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
