Inflammation and cognitive function in patients with metabolic syndrome

Autor: E. L Urumova, E. R. Baranzevich, I. B. Zueva, A. V. Butch, D. S. Krivonosov, A. Y. Smirnova
Rok vydání: 2017
Předmět:
Zdroj: Regional blood circulation and microcirculation. 16:38-42
ISSN: 1682-6655
DOI: 10.24884/1682-6655-2017-16-1-38-42
Popis: The purpose of this study was to explore the relationship between the level of C-reactive protein and fibrinogen, and indices of cognitive function in patients with metabolic syndrome. As a result of this study, it was demonstrated that patients with metabolic syndrome and cognitive impairment compared with the group without cognitive disorders was higher parameters of inflammation. The increase in C-reactive protein was associated with reduced memory and increased speed of reaction and ability to concentrate, whereas an increase in fibrinogen levels was associated with lower indicators of the processes of storing, preserving and reproduction of information, logical memory and orientation in time and space. Activation of inflammation could reflect one of the possible pathophysiological mechanisms that affect the development of cognitive deficits in patients with metabolic syndrome.
Databáze: OpenAIRE