Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability

Autor:	Karen L. Wright, Michael Larvin, Abdussalam Alhamoruni, Saoirse E. O'Sullivan
Rok vydání:	2012
Předmět:	Pharmacology Intestinal permeability Cannabinoid receptor Chemistry medicine.medical_treatment digestive oral and skin physiology Inflammation medicine.disease Endocannabinoid system medicine Gastric acid Tumor necrosis factor alpha Cannabinoid medicine.symptom Receptor
Zdroj:	British Journal of Pharmacology. 165:2598-2610
ISSN:	0007-1188
DOI:	10.1111/j.1476-5381.2011.01589.x
Popis:	Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion and intestinal motility. The ability to modulate intestinal permeability in inflammation may be important in therapy aimed at maintaining epithelial barrier integrity. The aim of the present study was to determine whether cannabinoids modulate the increased permeability associated with inflammation in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c742221e4575b50f3cb2f005d942b302 https://doi.org/10.1111/j.1476-5381.2011.01589.x Zobrazit plný text záznamu Plný text ve formátu PDF