Radioimmunoassay for mono-(2-ethylhexyl) phthalate in unextracted plasma

Autor: J D McKinney, P W Albro, G Clark, M I Luster, K Chae
Rok vydání: 1978
Předmět:
Zdroj: Clinical Chemistry. 24:429-432
ISSN: 1530-8561
0009-9147
DOI: 10.1093/clinchem/24.3.429
Popis: We report a radioimmunoassay for mono-(2-ethylhexyl) phthalate that has been coupled to a protein carrier as a radioligand. Competitive interference tests with a variety of related compounds indicated the assay to be highly specific. Quantitative comparison of mono-(2-ethylhexyl) phthalate values in plasma and serum samples between the radioimmunoassay and gas chromatographic procedures indicated a high reliability. Because this potentially toxic compound can leach into plasma from polyvinyl plastics, this assay should be particularly useful for those involved in the manufacture or use of medical devices made of them.
Databáze: OpenAIRE