Cardiac defibrillator implantation in patients with syncope and inducible ventricular arrhythmia: insights from the German DEVICE registry

Autor: A K Kahle, J Senges, M Hochadel, J Brachmann, D Thomas, F Straube, K Bonaventura, J Vom Dahl, N Werner, C Butter, K Scherschel, C Meyer
Rok vydání: 2023
Předmět:
Zdroj: Europace. 25
ISSN: 1532-2092
1099-5129
Popis: Funding Acknowledgements Type of funding sources: None. Background Programmed ventricular stimulation may be considered for risk stratification of sudden cardiac death. The history of syncope is an independent predictor for appropriate device discharge and sudden cardiac death, but data remain sparse among different populations. Purpose The aim of this study was to assess the prognostic value of previous syncope and inducible ventricular arrhythmia (VA) during programmed stimulation in patients undergoing defibrillator implantation. Methods Among 4,196 patients enrolled in the prospective, multi-centre German DEVICE Registry undergoing defibrillator implantation, patients with syncope and inducible VA (n=285, 6.8%) vs. those with a secondary preventive indication (n=1,885, 45.2%) serving as a control group were studied. In an additional analysis of patients with inducible VA, those with vs. without (n=86, 2.1%) previous syncope were compared. Results Patients with syncope and inducible VA (64.9±14.4 years, 81.1% male) presented less often with congestive heart failure (15.1% vs. 29.1%; P Conclusions Patients with a history of syncope and inducible VA present less frequently with most cardiac comorbidities resulting in better outcomes following defibrillator implantation than patients with a secondary preventive indication. Nevertheless, patients with inducible VA experience a relevant number of post-procedural adverse events not differing between those with vs. without syncope, which underlines the importance of VA inducibility, potentially irrespective of the history of syncope.
Databáze: OpenAIRE
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