Randomised controlled study with cyproterone acetate (100 mg/die) versus Pygeum africanum (200 mg/die) in benign prostatic hypertrophy

Autor:	A. Bono, F. Selvaggi, C. Consoli, E. Alcini, Michele Pavone-Macaluso, A. Zanollo, F. Micali, U. Jacobellis, L. Miano, P.P. Paoletti, M. Polito, T. Lotti
Rok vydání:	1994
Předmět:	chemistry.chemical_compound chemistry business.industry Cyproterone acetate Medicine Pygeum africanum General Medicine Pharmacology business Muscle hypertrophy
Zdroj:	Urologia Journal. 61:127-136
ISSN:	1724-6075 0391-5603
Popis:	A multi-centre comparative study was carried out on 143 patients with benign prostatic hypertrophy and reduced or no sexual activity. 74 patients were treated with a low dose of CPA (100 mg a day) and 69 with PYG (200 mg a day), administered orally and assigned randomly. The patients were evaluated at 4,12 and 24 weeks. Results showed a significant statistical difference in favour of the CPA treatment for almost all parameters (flow, post-micturitional residue, symptomatological score). There was a decrease in prostate volume, equal to 19.3% compared to the initial values, only in those patients treated with CPA who completed the treatment. Considerable improvement in nicturia and micturitional urgency was noted in about half the patients, without a significant difference between the two groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c723280c802e1e64ca6e7d638516fd5d https://doi.org/10.1177/039156039406100208 Zobrazit plný text záznamu