Antifungal Activity and Biological Characteristics of the Novel Fungicide Quinofumelin Against Sclerotinia sclerotiorum
| Autor: | Xiu-Shi Song, Yabing Duan, Zhongke Li, Mingguo Zhou, Xian Tao, Huahua Zhao, Haorong Xu, Jian-Xin Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
0301 basic medicine Antifungal medicine.drug_class Sclerotinia sclerotiorum Plant Science 030108 mycology & parasitology Biology biology.organism_classification 01 natural sciences Fungicide 03 medical and health sciences Horticulture medicine Agronomy and Crop Science Pathogen 010606 plant biology & botany |
| Zdroj: | Plant Disease. 105:2567-2574 |
| ISSN: | 1943-7692 0191-2917 |
| DOI: | 10.1094/pdis-08-20-1821-re |
| Popis: | Sclerotinia sclerotiorum is a devastating plant pathogen with a broad host range and worldwide distribution. The application of chemical fungicides is a primary strategy for controlling this pathogen. However, under the high selective pressure of chemical fungicides, fungicide resistance has emerged and gradually increased, resulting in the failure to control S. sclerotiorum in the field. Quinofumelin is a novel quinoline fungicide, but its antifungal activities against plant pathogens have been rarely reported. Here, we determined the antifungal activity of quinofumelin against S. sclerotiorum in vitro and in planta. The median effect concentration (EC50) values ranged from 0.0004 to 0.0059 µg ml−1 with a mean EC50 of 0.0017 ± 0.0009 µg ml−1 and were normally distributed (P = 0.402). In addition, no cross resistance was observed between quinofumelin and other fungicides, dimethachlone, boscalid, or carbendazim, which are commonly used to manage S. sclerotiorum. Quinofumelin did not affect glycerol and oxalic acid production of either carbendazim-sensitive or -resistant isolates. Moreover, quinofumelin exhibited excellent protective, curative, and translaminar activity against S. sclerotiorum on oilseed rape leaves. Protective activity was higher than curative activity. Interestingly, quinofumelin inhibited the formation of the infection cushion in S. sclerotiorum, which may contribute to the control efficacy of quinofumelin against S. sclerotiorum in the field. Our findings indicate that quinofumelin has excellent control efficacy against S. sclerotiorum in vitro and in planta as compared with extensively used fungicides and could be used to manage carbendazim- and dimethachlone-resistance in S. sclerotiorum in the field. |
| Databáze: | OpenAIRE |
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