Development of Nanoparticle Array Method by Using DNA Sequence Recognition Peptide
| Autor: | Daisuke Iwasaki, Shinji Katsura, Keijyu Yamazaki, Masahiko Oshige, Mieko Katsumata |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
Polymers and Plastics Atomic force microscopy Materials Science (miscellaneous) New materials Nanoparticle Nanotechnology Peptide Conjugated system DNA sequencing chemistry.chemical_compound chemistry Chemical Engineering (miscellaneous) Molecule DNA General Environmental Science |
| Zdroj: | KOBUNSHI RONBUNSHU. 65:493-495 |
| ISSN: | 1881-5685 0386-2186 |
| DOI: | 10.1295/koron.65.493 |
| Popis: | As nanotechnology has been developed, various nanoparticles and elemental device have been studied intensively. These studies suggest that new materials can be created by regular arranging of nanoparticles. However, a method for the arranging has not been developed sufficiently. We tried to arrange by using DNA molecules and the DNA sequences recognition peptide-conjugated nanoparticles. To achieve this goal, we investigated the following topics: 1) sample preparation of DNA sequence recognition peptide-conjugated nanoparticles; 2) complex formation of DNA and DNA sequence recognition peptide conjugated nanoparticles; 3) observation and evaluation of them by Atomic Force Microscope (AFM) techniques. We succeeded in the conjugation of the nanoparticle and the DNA sequence recognition peptide, the formation of the DNA and the peptide-conjugated nanoparticle complexes, and thearrangement of the nanoparticles in a target place on DNA. |
| Databáze: | OpenAIRE |
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