T Cell Costimulation by Derivatives of Benzoic Acid
Autor: | D Devine, Tony Ng, D. Kinchington, N Mathews, Michael J. Tisdale, Washington Odur Ayuko |
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Rok vydání: | 1997 |
Předmět: |
0301 basic medicine
medicine.drug_class Cell growth Lymphoblast T cell 030106 microbiology CD28 General Medicine T lymphocyte Biology Monoclonal antibody 01 natural sciences Molecular biology Peripheral blood mononuclear cell 0104 chemical sciences 010404 medicinal & biomolecular chemistry 03 medical and health sciences medicine.anatomical_structure Biochemistry medicine Cytotoxic T cell |
Zdroj: | Antiviral Chemistry and Chemotherapy. 8:121-130 |
ISSN: | 2040-2066 |
DOI: | 10.1177/095632029700800206 |
Popis: | A number of analogues of benzoic acid were evaluated in a T cell costimulation assay. One compound, the sodium salt of 2-chloro-5-nitrobenzoic acid (CNBA-Na) was chosen for further study and was found to be a potent costimulator of anti-CD3-induced proliferation of both H9 lymphoblastoid cells ( P |
Databáze: | OpenAIRE |
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